Bupleurum: A core synergistic herb targeted for PMS related mood changes 

Every ingredient we use is research backed. We found more than 523 studies on Bupleurum — here's what matters:
  • A powerful combination of peony root, bupleurum root, Chinese licorice root, and cyperus rhizome effectively improved the symptoms of PMS related depression, by helping to regulate Glu/GABA balance in the central nervous system, specifically by affecting neurotransmitters and receptors responsible for mood, memory, and other mental health conditions.
  • Has inhibitory effects on the central nervous system (Kanba S, Yamada K, Mizushima H, Murata T, Asai M. Use of herbal medicine for treating psychiatric disorders in Japan. In : KanbaS, RichelsonE (eds). Herbal Medicine for Neuropsychiatric Diseases. Seiwa Shoten/Brunner-Mazel, New York, 1999; 3–13.)